Epinephrine Bad for Long-Term Arrest Survival

By Crystal Phend, MedPage Today

For out-of-hospital cardiac arrest, administration of epinephrine on the way to the hospital initially improves the chances of resuscitation but hurts survival and function longer term, Japanese researchers found.

Circulation returned before arrival at the hospital for 18.5% of those given the adrenaline drug intravenously by paramedics, compared with 5.7% who didn't receive it (P<0.001) in a registry study by Akihito Hagihara, DMSc, MPH, of Kyushu University in Fukuoka, Japan, and colleagues.


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