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03/17/2025

ASCO Coding Tip of the Month

March 2025

With the emergence of multiple subcutaneous chemotherapy formulations of drugs originally formulated for intravenous infusion administration, it’s important to know the appropriate administration codes for these subcutaneous administrations. There are currently only two CPT® codes available to report subcutaneous chemotherapy administration. “Chemotherapy” administration may also apply to highly complex drugs and highly complex biologic agents. 

96401: Subcutaneous or intramuscular chemotherapy administration; non-hormonal
96402: Subcutaneous or intramuscular chemotherapy administration; hormonal

These codes are agnostic to time, which means time is not a factor in code selection. Refer to the latest publication of the CPT® Professional Edition for more information. 

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